Bone marrow transplant
A bone marrow transplant—more precisely, hematopoietic stem cell transplantation—is a medical procedure that replaces or rescues blood‑forming stem cells to reconstitute hematopoiesis and immunity. It is used to treat malignant and non‑malignant disorders, including leukemias, lymphomas, myelodysplastic syndromes, aplastic anemia, thalassemia, and sickle cell disease. Modern practice encompasses autologous, allogeneic, and syngeneic approaches with grafts sourced from peripheral blood, marrow, or umbilical cord blood, with outcomes continually improving through advances in conditioning, donor selection, and graft‑versus‑host disease prophylaxis.